Yohimbe

Yohimbe is derived from the bark of a West African tree. Side effects include nausea, insomnia, nervousness, and dizziness. Large doses of yohimbe can increase blood pressure and heart rate and may cause kidney failure. However, yohimbe has not been shown to be any better than placebo for enabling sexual intercourse.

Viramax is a commercial product that contains yohimbine, the active chemical ingredient of yohimbe, and three other herbs: catuaba, muira puama, and maca. It has not been proven to be either effective or safe, and interactions with medications are unknown

Gamma-Butyrolactone (GBL)

GBL is found in products marketed for improving sexual function (Verve and Jolt). This substance can convert to a chemical that can cause toxic and life-threatening effects, including seizures and even coma.

Gingko Biloba

Although the risks for gingko biloba appear to be low, there is an increased risk for bleeding at high doses and interaction with vitamin E, anti-clotting medications, and aspirin and other NSAIDs. Large doses can cause convulsions. Commercial gingko preparations have also been reported to contain colchicine, a substance that can be harmful in people with kidney or liver problems.

L-arginine (also called arginine)

Arginine may cause gastrointestinal problems. It can also lower blood pressure and change levels of certain chemicals and electrolytes in the body. It may increase the risk for bleeding. Some people have an allergic reaction to it, which in some cases may be severe. It may worsen asthma.

Dehydroepiandrosterone (DHEA)

DHEA is a supplement related to certain male and female hormones. Studies show inconclusive results in its treatment for ED. DHEA may interact dangerously with other medications.

Spanish Fly

Spanish fly, or cantharides, which is made from dried beetles, is the most widely-touted aphrodisiac but can be particularly harmful. It irritates the urinary and genital tract and can cause infection, scarring, and burning of the mouth and throat. In some cases, it can be life threatening. No one should try any aphrodisiac without consulting a doctor.

Because many cases of ED are due to reduced blood flow from blocked arteries, it is important to maintain the same healthy lifestyle habits used to prevent heart disease.

• Smoking. Smoking contributes to the development of ED, mainly because it increases the effects of other blood vessel disorders, including high blood pressure and atherosclerosis. 
• Alcohol Use. Heavy drinking can cause ED. Alcohol depresses the central nervous system and impairs sexual function. 
• Drug Abuse. Heroin, cocaine, methamphetamines, and marijuana can affect sexual function. 
• Weight and Sedentary Lifestyle. Obesity is a risk factor for ED. Lack of exercise and a sedentary lifestyle can lead to obesity and other health problems associated with ED. 
• Bicycle Riding. At this time, there is no adequate evidence that supports a relationship between bicycle riding and ED.
• Diet and Exercise.  Eat a heart-healthy diet rich in fresh fruits and vegetables, whole grains, and fibre and low in saturated fats and sodium. Because ED may be related to circulation problems, diets that benefit the heart are especially important.
• Weight Control.  Being overweight can contribute to ED. Try to achieve and maintain a healthy weight.
• Exercise.  Regular exercise is helpful for weight control, stress reduction, and a healthy heart.
• Alcohol and Smoking.  If you drink alcohol, do so in moderation. Alcohol abuse can contribute to ED. Quitting smoking is essential.
• Staying sexually active.  May help prevent ED. Frequent erections stimulate blood flow to the penis.
• Change or Reduce Medications. If medications are causing ED, discuss with your doctor whether to change to a different medication or reduce the dosage.